BARHL2 - BarH like homeobox 2 Gene

Homo sapiens

Gene ID: 343472 | Gene type: protein coding

About BARHL2

Cytogenetic location: 1p22.2 Genomic coordinates (GRCh38): 1:90,711,539-90,717,302 (from NCBI)

This gene has 1 transcript (splice variant), 205 orthologues and 3 paralogues. Restricted expression toward testis (RPKM 1.8).

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including generation of neurons; positive regulation of macromolecule biosynthetic process; and regulation of axon extension. Predicted to be part of chromatin. Predicted to be active in nucleus. Implicated in oral squamous cell carcinoma. Biomarker of colorectal cancer; oral squamous cell carcinoma; and stomach Cancer. [provided by Alliance of Genome Resources, Apr 2022]

BARHL2 Products(1)

mRNA	Protein	Name
NM_020063.2	NP_064447.1	barH-like 2 homeobox protein

BARHL2 Protein Structure

Homeobox

0
100
200
300
387 a.a.

Protein Preferred Names

Protein Names

barH-like 2 homeobox protein

Related Diseases

Diseases

Alias

Xeroderma Pigmentosum Group E

Xeroderma Pigmentosum, Group E	Xeroderma Pigmentosum V
Xp Group E	Xp5
Xpe	Xeroderma Pigmentosum, Complementation Group E

Oral Squamous Cell Carcinoma

Mouth Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Mouth

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01367	BARHL2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	BARHL2	VGNC	VGNC:38381
Felis catus	BARHL2	VGNC	VGNC:69109
Bos taurus	BARHL2	VGNC	VGNC:26422
Rattus norvegicus	BARHL2	RGD	RGD:620726
Macaca mulatta	BARHL2	VGNC	VGNC:70227
Mus musculus	BARHL2	MGD	MGI:1859314

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