Pip4k2b - phosphatidylinositol-5-phosphate 4-kinase, type II, beta Gene

Also Known as c11; Pip5k2b; PI5P4Kbeta

Species: Mus musculus

Gene Type: protein coding
Gene ID: 108083

Summary

Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity; protein homodimerization activity; and purine ribonucleoside triphosphate binding activity. Involved in autophagosome-lysosome fusion and regulation of Autophagy. Acts upstream of or within phosphatidylinositol metabolic process. Predicted to be located in autophagosome; nucleoplasm; and plasma membrane. Is expressed in head bone; nervous system; and sensory organ. Orthologous to human PIP4K2B (phosphatidylinositol-5-phosphate 4-kinase type 2 beta). [provided by Alliance of Genome Resources, Apr 2022]

Pip4k2b Products (1)

mRNA Protein Name
NM_054051.1 NP_473392.1 phosphatidylinositol 5-phosphate 4-kinase type-2 beta

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9038203 MGI
Biological Process GO Annotation Evidence References Source
involved in autophagosome-lysosome fusion IMP
IMP: Inferred from mutant phenotype
29727621 MGI
acts upstream of or within phosphatidylinositol metabolic process IDA
IDA: Inferred from direct assay
9038203 MGI
involved in regulation of autophagy IMP
IMP: Inferred from mutant phenotype
29727621 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylinositol 5-phosphate 4-kinase type-2 beta

  • 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta

  • PI(5)P 4-kinase type II beta

  • PIP4KII-beta

  • diphosphoinositide kinase 2-beta

  • phosphatidylinositol-4-phosphate 5-kinase, type II, beta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-177432 TMX-4140 Inhibitor / Unkown
HY-183627 066ATZ Inhibitor / Unkown
HY-RS10563 PIP4K2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pip4k2b NCBI NCBI:8396