2. Gene
  3. PIP4K2B - phosphatidylinositol-5-phosphate 4-kinase type 2 beta Gene

PIP4K2B - phosphatidylinositol-5-phosphate 4-kinase type 2 beta Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PI5P4KB; PIP5K2B; PIP5KIIB; PIP5P4KB; PIP5KIIbeta

Gene ID: 8396 | Gene type: protein coding

About PIP4K2B

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:38,765,691-38,799,556 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 191 orthologues and 6 paralogues. Ubiquitous expression in brain (RPKM 40.4), ovary (RPKM 23.8) and 24 other tissues.

Summary

The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF Receptor. [provided by RefSeq, Jul 2008]

PIP4K2B Products(1)

mRNA Protein Name
NM_003559.5 NP_003550.1 phosphatidylinositol 5-phosphate 4-kinase type-2 beta

PIP4K2B Protein Structure

PIP5K

PIP5K: Phosphatidylinositol-4-phosphate 5-Kinase (129 - 414)

  • 0
  • 100
  • 200
  • 300
  • 416 a.a.
Protein Preferred Names Protein Names

phosphatidylinositol 5-phosphate 4-kinase type-2 beta

1-phosphatidylinositol 5-phosphate 4-kinase 2-beta

Recombinant PIP4K2B Proteins

Cat. No. Product Name Accession Purity
HY-P700597 PIP4K2B Protein, Human (His) P78356 (S2-T416) ≥95%

Related Diseases

Diseases Alias
Developmental And Epileptic Encephalopathy 33

DEE33

Epileptic Encephalopathy, Early Infantile, 33

Eiee33

Developmental And Epileptic Encephalopathy, 33

Early Infantile Epileptic Encephalopathy 33

Encephalopathy, Epileptic, Early Infantile, Type 33
Cone-Rod Dystrophy 5

CORD5

Dystrophy, Cone-Rod, Type 5
Lateral Meningocele Syndrome

Lehman Syndrome

Lms

LMNS

Meningocele, Lateral Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10563 PIP4K2B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PIP4K2B VGNC VGNC:32907
Macaca mulatta PIP4K2B VGNC VGNC:76004
Rattus norvegicus PIP4K2B RGD RGD:621710
Felis catus PIP4K2B VGNC VGNC:68865
Mus musculus PIP4K2B MGD MGI:1934234
Canis familiaris PIP4K2B VGNC VGNC:44571
Others PIP4K2B NCBI