C1QL1 - complement C1q like 1 Gene

Also Known as CRF; C1QRF; CTRP14; C1QTNF14

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10882

About C1QL1

Cytogenetic location: 17q21.31 Genomic coordinates (GRCh38): 17:44,959,693-44,968,303 (from NCBI)

This gene has 1 transcript (splice variant), 179 orthologues and 23 paralogues. Biased expression in brain (RPKM 10.8), kidney (RPKM 1.7) and 4 other tissues.

Summary

Predicted to enable signaling receptor binding activity. Predicted to act upstream of or within maintenance of synapse structure; motor learning; and neuron remodeling. Predicted to be located in several cellular components, including climbing fiber; presynapse; and synaptic cleft. Predicted to be part of Collagen trimer. [provided by Alliance of Genome Resources, Apr 2022]

C1QL1 Products (1)

mRNA Protein Name
NM_006688.5 NP_006679.1 C1q-related factor precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19666007 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

C1QL1 Protein Structure

Collagen

Collagen: Collagen triple helix repeat (20 copies) (67 - 115)

C1q

C1q: C1q domain (131 - 255)

  • 0
  • 100
  • 200
  • 258 a.a.
Protein Preferred Names Protein Names

C1q-related factor

  • C1q and tumor necrosis factor-related protein 14

C1QL1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
C1QL1 O75973 C1QTNF8 Homo sapiens P60827
Anti Tag CoIP
19666007
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01722 C1QL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21500 C1ql1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28018 C1ql1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus C1QL1 MGD MGI:1344400
Bos taurus C1QL1 VGNC VGNC:26620
Macaca mulatta C1QL1 VGNC VGNC:70372
Rattus norvegicus C1QL1 RGD RGD:1306039
Felis catus C1QL1 VGNC VGNC:98773
Canis familiaris C1QL1 VGNC VGNC:38579
Others C1QL1 NCBI