2. Gene
  3. Grik4 - glutamate receptor, ionotropic, kainate 4 Gene

Grik4 - glutamate receptor, ionotropic, kainate 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as KA1; KA-1; GluK4; GluRgamma1; 6330551K01Rik

Gene ID: 110637 | Gene type: protein coding

About Grik4

Summary

Predicted to enable kainate selective glutamate receptor activity and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to act upstream of or within ion transport. Located in postsynaptic membrane and presynaptic membrane. Is integral component of postsynaptic membrane. Part of kainate selective glutamate receptor complex. Is active in hippocampal mossy fiber to CA3 synapse. Is integral component of presynaptic membrane. Is expressed in brain; retina; and spinal cord. Orthologous to human GRIK4 (glutamate ionotropic receptor kainate type subunit 4). [provided by Alliance of Genome Resources, Apr 2022]

Grik4 Products(1)

mRNA Protein Name
NM_175481.5 NP_780690.2 glutamate receptor ionotropic, kainate 4 precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12954862 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: Inferred from direct assay
12954862 MGI
part of kainate selective glutamate receptor complex IPI
IPI: Inferred from physical interaction
12954862 MGI
located in membrane IDA
IDA: Inferred from direct assay
12954862 MGI
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
12954862 MGI
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
12954862 MGI
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
12954862 MGI
located in presynaptic membrane IDA
IDA: Inferred from direct assay
12954862 MGI
located in synapse IDA
IDA: Inferred from direct assay
21734292 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutamate receptor ionotropic, kainate 4

glutamate receptor KA1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05801 GRIK4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grik4 NCBI NCBI:2900