Grik4 - glutamate receptor, ionotropic, kainate 4 Gene

Predicted to enable kainate selective glutamate receptor activity and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to act upstream of or within ion transport. Located in postsynaptic membrane and presynaptic membrane. Is integral component of postsynaptic membrane. Part of kainate selective glutamate receptor complex. Is active in hippocampal mossy fiber to CA3 synapse. Is integral component of presynaptic membrane. Is expressed in brain; retina; and spinal cord. Orthologous to human GRIK4 (glutamate ionotropic receptor kainate type subunit 4). [provided by Alliance of Genome Resources, Apr 2022]