2. Gene
  3. P2rx5 - purinergic receptor P2X 5 Gene

P2rx5 - purinergic receptor P2X 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as P2x5

Gene ID: 113995 | Gene type: protein coding

About P2rx5

Summary

Enables ATP binding activity; gated channel activity; and identical protein binding activity. Involved in several processes, including positive regulation of calcium ion import across plasma membrane; regulation of skeletal muscle tissue regeneration; and response to ATP. Located in plasma membrane. Orthologous to human P2RX5 (purinergic receptor P2X 5). [provided by Alliance of Genome Resources, Apr 2022]

P2rx5 Products(1)

mRNA Protein Name
NM_080780.3 NP_542958.3 P2X purinoceptor 5
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables ATP binding IDA
IDA: Inferred from direct assay
12237343 RGD
enables ATP-gated ion channel activity IDA
IDA: Inferred from direct assay
8786426 RGD
enables extracellularly ATP-gated monoatomic cation channel activity IDA
IDA: Inferred from direct assay
12135987 RGD
enables identical protein binding IDA
IDA: Inferred from direct assay
17001079 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
15313628 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9855626 RGD
enables voltage-gated monoatomic ion channel activity IDA
IDA: Inferred from direct assay
12237343 RGD
Biological Process GO Annotation Evidence Reference Source
involved in monoatomic cation transmembrane transport IDA
IDA: Inferred from direct assay
12237343 RGD
involved in positive regulation of calcium ion import across plasma membrane IDA
IDA: Inferred from direct assay
12237343 RGD
involved in regulation of skeletal muscle tissue regeneration IMP
IMP: Inferred from mutant phenotype
12135987 RGD
involved in response to ATP IDA
IDA: Inferred from direct assay
12237343 RGD
involved in response to calcium ion IDA
IDA: Inferred from direct assay
12237343 RGD
involved in response to pH IDA
IDA: Inferred from direct assay
12237343 RGD
involved in response to zinc ion IDA
IDA: Inferred from direct assay
12237343 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

P2X purinoceptor 5

ATP receptor

purinergic receptor P2X, ligand-gated ion channel, 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09909 P2RX5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens P2rx5 NCBI NCBI:5026