SARDH - Sardh sarcosine dehydrogenase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114123

Summary

Enables flavin adenine dinucleotide binding activity; folic acid binding activity; and sarcosine dehydrogenase activity. Involved in tetrahydrofolate interconversion. Located in mitochondrial matrix. Human ortholog(s) of this gene implicated in sarcosinemia. Orthologous to human SARDH (sarcosine dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

SARDH Products (1)

mRNA Protein Name
NM_053664.2 NP_446116.1 sarcosine dehydrogenase, mitochondrial

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables flavin adenine dinucleotide binding IDA
IDA: Inferred from direct assay
6163778 RGD
enables folic acid binding IDA
IDA: Inferred from direct assay
6163778 RGD
enables sarcosine dehydrogenase activity IDA
IDA: Inferred from direct assay
6163778 RGD
Biological Process GO Annotation Evidence References Source
involved in tetrahydrofolate interconversion IDA
IDA: Inferred from direct assay
6163778 RGD
Cellular Component GO Annotation Evidence References Source
located in mitochondrial matrix IDA
IDA: Inferred from direct assay
9839943 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sarcosine dehydrogenase, mitochondrial

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12445 SARDH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22795 Sardh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29309 Sardh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SARDH NCBI NCBI:1757