Chrng - cholinergic receptor, nicotinic, gamma polypeptide Gene

Also Known as Acrg; Achr-3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11449

Summary

Enables acetylcholine-gated cation-selective channel activity. Acts upstream of or within regulation of membrane potential. Located in postsynaptic membrane. Part of acetylcholine-gated channel complex. Is expressed in several structures, including diaphragm; embryo mesenchyme; limb bud; skeletal musculature; and tongue. Human ortholog(s) of this gene implicated in multiple pterygium syndrome. Orthologous to human CHRNG (cholinergic receptor nicotinic gamma subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrng Products (2)

mRNA Protein Name
NM_001411849.1 NP_001398778.1 acetylcholine receptor subunit gamma isoform 2 precursor
NM_009604.4 NP_033734.3 acetylcholine receptor subunit gamma isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acetylcholine-gated monoatomic cation-selective channel activity IGI
IGI: Inferred from genetic interaction
2383398 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8798466 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of membrane potential IGI
IGI: Inferred from genetic interaction
2383398 MGI
Cellular Component GO Annotation Evidence References Source
part of acetylcholine-gated channel complex IDA
IDA: Inferred from direct assay
8798466 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12388596 MGI
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
15883046 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acetylcholine receptor subunit gamma

  • nicotinic acetylcholine receptor gamma subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02680 CHRNG Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chrng NCBI NCBI:1146