Strn3 - striatin 3 Gene

Rattus norvegicus

Also known as Gs2na; Sg2na

Gene ID: 114520 | Gene type: protein coding

About Strn3

Summary

Predicted to enable armadillo repeat domain binding activity; Calmodulin binding activity; and enzyme binding activity. Involved in negative regulation of intracellular Estrogen receptor signaling pathway; negative regulation of transcription, DNA-templated; and response to estradiol. Located in cytoplasm; dendrite; and neuronal cell body. Part of protein-containing complex. Orthologous to human STRN3 (striatin 3). [provided by Alliance of Genome Resources, Apr 2022]

Strn3 Products(1)

mRNA	Protein	Name
NM_001029897.3	NP_001025068.1	striatin-3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	11251078	RGD
enables protein-containing complex binding	IDA IDA: Inferred from direct assay	18434427	RGD
enables protein-containing complex binding	IPI IPI: Inferred from physical interaction	16445688	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of DNA-templated transcription	IMP IMP: Inferred from mutant phenotype	18434427	RGD
involved in negative regulation of intracellular estrogen receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	18434427	RGD
involved in response to estradiol	IDA IDA: Inferred from direct assay	18434427	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in dendrite	IDA IDA: Inferred from direct assay	10748158	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	12610732	RGD
part of protein-containing complex	IDA IDA: Inferred from direct assay	18434427	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

striatin-3

cell cycle autoantigen SG2NA	nuclear autoantigen
s/G2 antigen	striatin, calmodulin binding protein 3
striatin-3-gamma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13967	STRN3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Strn3	NCBI	NCBI:29966

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