Suclg1 - succinate-CoA ligase GDP/ADP-forming subunit alpha Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114597

Summary

Enables GDP binding activity; succinate-CoA Ligase (ADP-forming) activity; and succinate-CoA Ligase (GDP-forming) activity. Involved in succinate metabolic process; succinyl-CoA metabolic process; and tricarboxylic acid cycle. Located in mitochondrion. Part of succinate-CoA Ligase complex (GDP-forming). Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 9. Orthologous to human SUCLG1 (succinate-CoA Ligase GDP/ADP-forming subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Suclg1 Products (1)

mRNA Protein Name
NM_053752.2 NP_446204.2 succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GDP binding IDA
IDA: Inferred from direct assay
7430155 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
7430155 RGD
enables succinate-CoA ligase (ADP-forming) activity IDA
IDA: Inferred from direct assay
17403370 RGD
enables succinate-CoA ligase (GDP-forming) activity IDA
IDA: Inferred from direct assay
7430155 RGD
Biological Process GO Annotation Evidence References Source
involved in succinate metabolic process IDA
IDA: Inferred from direct assay
17403370 RGD
involved in succinyl-CoA metabolic process IDA
IDA: Inferred from direct assay
7430155 RGD
involved in tricarboxylic acid cycle IDA
IDA: Inferred from direct assay
17403370 RGD
Cellular Component GO Annotation Evidence References Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
11831846 RGD
part of succinate-CoA ligase complex (GDP-forming) IDA
IDA: Inferred from direct assay
7430155 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

  • SCS-alpha

  • succinate-CoA ligase, GDP-forming alpha subunit

  • succinate-CoA ligase, alpha subunit

  • succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

  • succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial

  • succinyl-CoA synthetase al

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70121 Succinyl-CoA synthetase / Unkown
HY-RS14001 SUCLG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21202 Suclg1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27718 Suclg1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Suclg1 NCBI NCBI:8802