Prdm15 - PR domain containing 15 Gene
Also Known as ORF62; Zfp298; C21orf83; E130018M06Rik
Species: Mus musculus
Summary
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and promoter-specific chromatin binding activity. Involved in positive regulation of transcription by RNA polymerase II; regulation of signal transduction; and regulation of stem cell division. Located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; incisor; sensory organ; and skin. Orthologous to human PRDM15 (PR/SET domain 15). [provided by Alliance of Genome Resources, Apr 2022]
Prdm15 Products (12)
| mRNA | Protein | Name |
|---|---|---|
| NM_001359077.2 | NP_001346006.1 | PR domain zinc finger protein 15 isoform 2 |
| NM_001359078.2 | NP_001346007.1 | PR domain zinc finger protein 15 isoform 3 |
| NM_001403426.1 | NP_001390355.1 | PR domain zinc finger protein 15 isoform 2 |
| NM_001403427.1 | NP_001390356.1 | PR domain zinc finger protein 15 isoform 4 |
| NM_001403428.1 | NP_001390357.1 | PR domain zinc finger protein 15 isoform 4 |
| NM_001403429.1 | NP_001390358.1 | PR domain zinc finger protein 15 isoform 5 |
| NM_001403430.1 | NP_001390359.1 | PR domain zinc finger protein 15 isoform 6 |
| NM_001403431.1 | NP_001390360.1 | PR domain zinc finger protein 15 isoform 7 |
| NM_001403432.1 | NP_001390361.1 | PR domain zinc finger protein 15 isoform 8 |
| NM_001403437.1 | NP_001390366.1 | PR domain zinc finger protein 15 isoform 9 |
| NM_001403438.1 | NP_001390367.1 | PR domain zinc finger protein 15 isoform 10 |
| NM_144789.2 | NP_659038.2 | PR domain zinc finger protein 15 isoform 1 |
| Molecular Function GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| enables RNA polymerase II cis-regulatory region sequence-specific DNA binding |
IDA
IDA: Inferred from direct assay
|
28740264 | MGI |
| enables promoter-specific chromatin binding |
IDA
IDA: Inferred from direct assay
|
28740264 | MGI |
| Biological Process GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| involved in negative regulation of MAPK cascade |
IMP
IMP: Inferred from mutant phenotype
|
28740264 | MGI |
| involved in positive regulation of canonical Wnt signaling pathway |
IMP
IMP: Inferred from mutant phenotype
|
28740264 | MGI |
| involved in positive regulation of transcription by RNA polymerase II |
IDA
IDA: Inferred from direct assay
|
28740264 | MGI |
| involved in regulation of stem cell division |
IMP
IMP: Inferred from mutant phenotype
|
28740264 | MGI |
| Cellular Component GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
28740264 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
PR domain zinc finger protein 15 |
|