Plce1 - phospholipase C, epsilon 1 Gene

Also Known as Plce

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114633

Summary

Enables phosphatidylinositol Phospholipase C activity and small GTPase binding activity. Involved in G protein-coupled receptor signaling pathway and Ras protein signal transduction. Located in cytoplasm. Human ortholog(s) of this gene implicated in nephrotic syndrome; nephrotic syndrome type 2; and nephrotic syndrome type 3. Orthologous to human PLCE1 (Phospholipase C epsilon 1). [provided by Alliance of Genome Resources, Apr 2022]

Plce1 Products (1)

mRNA Protein Name
NM_053758.2 NP_446210.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables phosphatidylinositol phospholipase C activity IDA
IDA: Inferred from direct assay
11179219 RGD
enables small GTPase binding IDA
IDA: Inferred from direct assay
11179219 RGD
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
16314422 RGD
involved in Ras protein signal transduction IDA
IDA: Inferred from direct assay
11179219 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

  • PLC-epsilon-1

  • phosphoinositide phospholipase C-epsilon-1

  • phosphoinositide-specific phospholipase C epsilon-1

  • phospholipase C epsilon

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10659 PLCE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plce1 NCBI NCBI:51196