2. Gene
  3. Plce1 - phospholipase C, epsilon 1 Gene

Plce1 - phospholipase C, epsilon 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Plce

Gene ID: 114633 | Gene type: protein coding

About Plce1

Summary

Enables phosphatidylinositol Phospholipase C activity and small GTPase binding activity. Involved in G protein-coupled receptor signaling pathway and Ras protein signal transduction. Located in cytoplasm. Human ortholog(s) of this gene implicated in nephrotic syndrome; nephrotic syndrome type 2; and nephrotic syndrome type 3. Orthologous to human PLCE1 (Phospholipase C epsilon 1). [provided by Alliance of Genome Resources, Apr 2022]

Plce1 Products(1)

mRNA Protein Name
NM_053758.2 NP_446210.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables phosphatidylinositol phospholipase C activity IDA
IDA: Inferred from direct assay
11179219 RGD
enables small GTPase binding IDA
IDA: Inferred from direct assay
11179219 RGD
Biological Process GO Annotation Evidence Reference Source
involved in G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
16314422 RGD
involved in Ras protein signal transduction IDA
IDA: Inferred from direct assay
11179219 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

PLC-epsilon-1

phosphoinositide phospholipase C-epsilon-1

phosphoinositide-specific phospholipase C epsilon-1

phospholipase C epsilon

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10659 PLCE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plce1 NCBI NCBI:51196