Cygb - cytoglobin Gene

Also Known as HGb; Staap; 3110001K20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 114886

Summary

Predicted to enable catalase activity; fatty acid peroxidase activity; and heme binding activity. Predicted to be involved in several processes, including negative regulation of Collagen biosynthetic process; negative regulation of fibroblast migration; and negative regulation of hepatic stellate cell activation. Predicted to act upstream of or within oxygen transport. Located in neuron projection and neuronal cell body. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; head mesenchyme; and sensory organ. Orthologous to human CYGB (cytoglobin). [provided by Alliance of Genome Resources, Apr 2022]

Cygb Products (1)

mRNA Protein Name
NM_030206.4 NP_084482.1 cytoglobin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables nitric oxide dioxygenase activity, heme protein as donor IDA
IDA: Inferred from direct assay
33334890 MGI
enables superoxide dismutase activity IMP
IMP: Inferred from mutant phenotype
34930834 MGI
Biological Process GO Annotation Evidence References Source
involved in nitric oxide catabolic process IDA
IDA: Inferred from direct assay
33334890 MGI
involved in nitric oxide catabolic process IMP
IMP: Inferred from mutant phenotype
28393874 MGI
involved in removal of superoxide radicals IMP
IMP: Inferred from mutant phenotype
34930834 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytoplasm IDA
IDA: Inferred from direct assay
34930834 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
14660570 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
14660570 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
14660570 MGI
located in nucleus IDA
IDA: Inferred from direct assay
14660570 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytoglobin

  • histoglobin

  • stellate cell activation associated protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03432 CYGB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18031 Cygb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24505 Cygb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cygb NCBI NCBI:114757