Adam5 - a disintegrin and metallopeptidase domain 5 Gene

Also Known as tMDCII; tMDC II

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11499

Summary

This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. This gene is located in a cluster of related ADAM genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing. [provided by RefSeq, May 2016]

Adam5 Products (4)

mRNA Protein Name
NM_001272057.1 NP_001258986.1 disintegrin and metalloproteinase domain-containing protein 5 isoform 2 precursor
NM_001272058.1 NP_001258987.1 disintegrin and metalloproteinase domain-containing protein 5 isoform 1 precursor
NM_001272059.1 NP_001258988.1 disintegrin and metalloproteinase domain-containing protein 5 isoform 4 precursor
NM_007401.3 NP_031427.2 disintegrin and metalloproteinase domain-containing protein 5 isoform 3 preproprotein

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23969891 MGI
Cellular Component GO Annotation Evidence References Source
is active in cell surface IDA
IDA: Inferred from direct assay
16407499 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

disintegrin and metalloproteinase domain-containing protein 5

  • a disintegrin and metalloprotease domain (ADAM) 5

  • transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein II

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (19)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P10174A ADAM-17 Substrate TFA 98.19% Unkown
HY-132917 ADAM8-IN-1 Inhibitor 98.30% Unkown
HY-175876 ADAM17-IN-1 Inhibitor / Unkown
HY-P10174 ADAM-17 Substrate / Unkown
HY-RS00270 ADAM15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00276 ADAM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00285 ADAM7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00286 ADAM8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00287 Adam8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00288 Adam8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00289 ADAM9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00388 ADM5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-156407 Adam-20-S Inhibitor / Unkown
HY-RS17598 Adam9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18692 Adam15 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22377 Adam2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24058 Adam9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25179 Adam15 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28901 Adam2 Rat Pre-designed siRNA Set A / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992185 Anti-ADAM17 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adam5 NCBI NCBI:255926