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Cat. No.: HY-156407

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Adam-20-S

Adam-20-S is a potent glucosinolate sulfatase inhibitor with an IC₅₀ value of 9.04 μg/mL. Adam-20-S impaires glucosinolate metabolism to produce more toxic isothiocyanates in P. xylostella.

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CAS No.: 2413880-52-9
Formule: C₁₇H₂₁FN₂O₄S
Masse moléculaire:368.42

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Adam-20-S Chemical Structure

CAS No.: 2413880-52-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

IC₅₀ & Target

IC₅₀：9.04 μg/mL^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
JEG-3	IC₅₀	67.7 nM Compound: 1p	Inhibition of steroid sulfatase in human JEG3 cell lysates using [3H] E1S as substrate after 1 hr by scintillation spectrometry analysis Inhibition of steroid sulfatase in human JEG3 cell lysates using [3H] E1S as substrate after 1 hr by scintillation spectrometry analysis	[PMID: 32173116]
T47D	IC₅₀	3.4 μM Compound: 1p	Antiproliferative activity against human T47D cells assessed as reduction in cell proliferation measured after 5 days in presence of estradiol sulfate by crystal violet staining based assay Antiproliferative activity against human T47D cells assessed as reduction in cell proliferation measured after 5 days in presence of estradiol sulfate by crystal violet staining based assay	[PMID: 32173116]

Chemical Information

CAS No. 2413880-52-9
Masse moléculaire 368.42
Formule C₁₇H₂₁FN₂O₄S
SMILES

FC1=CC(C(NC2(C3)CC4CC3CC(C2)C4)=O)=CC=C1OS(N)(=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Dehong L,et al. Synthesis and Biological Activity of Sulfamate-Adamantane Derivatives as Glucosinolate Sulfatase Inhibitors. 2023 Oct 25;71(42):15476-15484. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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