Adra1b - adrenergic receptor, alpha 1b Gene

Also Known as [a]1b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11548

Summary

Enables alpha1-adrenergic receptor activity. Involved in multicellular organism aging; neuron-glial cell signaling; and regulation of blood pressure. Acts upstream of or within several processes, including positive regulation of blood pressure; regulation of glycogen catabolic process; and response to alkaloid. Is integral component of membrane. Is expressed in central nervous system; heart; retina; and testis. Orthologous to human ADRA1B (adrenoceptor alpha 1B). [provided by Alliance of Genome Resources, Apr 2022]

Adra1b Products (3)

mRNA Protein Name
NM_001284380.1 NP_001271309.1 alpha-1B adrenergic receptor
NM_001284381.1 NP_001271310.1 alpha-1B adrenergic receptor
NM_007416.4 NP_031442.2 alpha-1B adrenergic receptor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables alpha1-adrenergic receptor activity IDA
IDA: Inferred from direct assay
7911220 MGI
enables alpha1-adrenergic receptor activity IGI
IGI: Inferred from genetic interaction
12782680 MGI
enables alpha1-adrenergic receptor activity IMP
IMP: Inferred from mutant phenotype
9326654 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within adult heart development IGI
IGI: Inferred from genetic interaction
12782680 MGI
acts upstream of or within behavioral response to cocaine IMP
IMP: Inferred from mutant phenotype
11923452 MGI
acts upstream of or within blood vessel remodeling IMP
IMP: Inferred from mutant phenotype
15231500 MGI
acts upstream of or within cell growth involved in cardiac muscle cell development IGI
IGI: Inferred from genetic interaction
12782680 MGI
acts upstream of or within glucose homeostasis IMP
IMP: Inferred from mutant phenotype
14581480 MGI
acts upstream of glycogen catabolic process IMP
IMP: Inferred from mutant phenotype
14581480 MGI
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
11222061 MGI
acts upstream of or within negative regulation of glycogen catabolic process IMP
IMP: Inferred from mutant phenotype
14581480 MGI
involved in neuron-glial cell signaling IGI
IGI: Inferred from genetic interaction
10493741 MGI
acts upstream of or within organ growth IGI
IGI: Inferred from genetic interaction
12782680 MGI
acts upstream of or within positive regulation of glycogen catabolic process IMP
IMP: Inferred from mutant phenotype
14581480 MGI
acts upstream of or within positive regulation of heart rate by epinephrine-norepinephrine IGI
IGI: Inferred from genetic interaction
12782680 MGI
acts upstream of or within positive regulation of the force of heart contraction by epinephrine-norepinephrine IGI
IGI: Inferred from genetic interaction
12595294 MGI
involved in regulation of blood pressure IMP
IMP: Inferred from mutant phenotype
26531127 MGI
acts upstream of or within response to amphetamine IMP
IMP: Inferred from mutant phenotype
11923452 MGI
acts upstream of or within response to morphine IMP
IMP: Inferred from mutant phenotype
11923452 MGI
acts upstream of or within vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure IMP
IMP: Inferred from mutant phenotype
9326654 MGI
acts upstream of or within visual learning IMP
IMP: Inferred from mutant phenotype
11222061 MGI
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
11923452 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-1B adrenergic receptor

  • alpha-1B adrenoceptor

  • alpha-1B adrenoreceptor

  • alpha1B-adrenergic receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00409 ADRA1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adra1b NCBI NCBI:147