TJP2 - Tjp2 tight junction protein 2 Gene

Also Known as ZO-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 115769

Summary

Enables protein C-terminus binding activity. Involved in response to organic substance. Located in bicellular tight junction. Biomarker of hypertension. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 51; disease of metabolism; and progressive familial intrahepatic cholestasis 4. Orthologous to human TJP2 (tight junction protein 2). [provided by Alliance of Genome Resources, Apr 2022]

TJP2 Products (2)

mRNA Protein Name
NM_001414504.1 NP_001401433.1 tight junction protein ZO-2 isoform 1
NM_053773.3 NP_446225.1 tight junction protein ZO-2 isoform 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables transmembrane transporter binding IPI
IPI: Inferred from physical interaction
15980428 RGD
Cellular Component GO Annotation Evidence References Source
located in bicellular tight junction IDA
IDA: Inferred from direct assay
10559001 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tight junction protein ZO-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14554 TJP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22344 Tjp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens TJP2 NCBI NCBI:9414