Gripap1 - GRIP1 associated protein 1 Gene

Also Known as Grasp1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116493

Summary

Predicted to enable identical protein binding activity. Involved in neurotransmitter receptor transport, endosome to postsynaptic membrane; regulation of intracellular transport; and regulation of modification of synaptic structure. Located in postsynaptic recycling endosome. Is active in glutamatergic synapse. Is extrinsic component of postsynaptic early endosome membrane. Orthologous to human GRIPAP1 (GRIP1 associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Gripap1 Products (1)

mRNA Protein Name
NM_053807.2 NP_446259.1 GRIP1-associated protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables guanyl-nucleotide exchange factor activity IMP
IMP: Inferred from mutant phenotype
10896157 RGD
enables ionotropic glutamate receptor binding IPI
IPI: Inferred from physical interaction
10896157 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10896157 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of protein localization IMP
IMP: Inferred from mutant phenotype
10896157 RGD
involved in negative regulation of receptor clustering IMP
IMP: Inferred from mutant phenotype
10896157 RGD
involved in regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane IDA
IDA: Inferred from direct assay
20098723 RGD
involved in regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane IMP
IMP: Inferred from mutant phenotype
20098723 RGD
involved in regulation of recycling endosome localization within postsynapse IDA
IDA: Inferred from direct assay
20098723 RGD
involved in regulation of recycling endosome localization within postsynapse IMP
IMP: Inferred from mutant phenotype
20098723 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
10896157 RGD
is active in extrinsic component of postsynaptic early endosome membrane IDA
IDA: Inferred from direct assay
20098723 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
20098723 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
20098723 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
10896157 RGD
located in presynaptic membrane IDA
IDA: Inferred from direct assay
10896157 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GRIP1-associated protein 1

  • GRASP-1

  • GRIP-associated protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05811 GRIPAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gripap1 NCBI NCBI:56850