Kynu - kynureninase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116682

Summary

Enables kynureninase activity and pyridoxal phosphate binding activity. Involved in aging and tryptophan catabolic process to acetyl-CoA. Located in cytosol. Used to study hypertension. Human ortholog(s) of this gene implicated in hydroxykynureninuria. Orthologous to human KYNU (kynureninase). [provided by Alliance of Genome Resources, Apr 2022]

Kynu Products (1)

mRNA Protein Name
NM_053902.2 NP_446354.1 kynureninase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables kynureninase activity IDA
IDA: Inferred from direct assay
3400092 RGD
enables pyridoxal phosphate binding IDA
IDA: Inferred from direct assay
7451426 RGD
Biological Process GO Annotation Evidence References Source
involved in tryptophan catabolic process to acetyl-CoA IDA
IDA: Inferred from direct assay
7236232 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kynureninase

  • L-kynurenine hydrolase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS17219 Kynu Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07480 KYNU Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23671 Kynu Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kynu NCBI NCBI:8942