Pabpn1 - poly(A) binding protein, nuclear 1 Gene

Rattus norvegicus

Gene ID: 116697 | Gene type: protein coding

About Pabpn1

Summary

Predicted to enable RNA polymerase binding activity. Predicted to be involved in several processes, including cellular response to lipopolysaccharide; poly(A)+ mRNA export from nucleus; and positive regulation of polynucleotide adenylyltransferase activity. Located in nuclear inclusion body. Human ortholog(s) of this gene implicated in oculopharyngeal muscular dystrophy. Orthologous to human PABPN1 (poly(A) binding protein nuclear 1). [provided by Alliance of Genome Resources, Apr 2022]

Pabpn1 Products(1)

mRNA	Protein	Name
NM_001135008.1	NP_001128480.1	polyadenylate-binding protein 2

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
located in nuclear inclusion body	IDA IDA: Inferred from direct assay	18255312	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

polyadenylate-binding protein 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09952	PABPN1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pabpn1	NCBI	NCBI:8106

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