2. Gene
  3. Myo1b - myosin Ib Gene

Myo1b - myosin Ib Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Myr1

Gene ID: 117057 | Gene type: protein coding

About Myo1b

Summary

Enables several functions, including actin filament binding activity; anion binding activity; and Calmodulin binding activity. Involved in actin filament bundle assembly and actin filament-based movement. Located in several cellular components, including apical part of cell; brush border; and filopodium. Orthologous to human MYO1B (Myosin IB). [provided by Alliance of Genome Resources, Apr 2022]

Myo1b Products(1)

mRNA Protein Name
NM_053986.2 NP_446438.1 unconventional myosin-Ib
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables ATP binding IDA
IDA: Inferred from direct assay
17298083 RGD
enables actin binding IDA
IDA: Inferred from direct assay
20080738 RGD
enables actin filament binding IDA
IDA: Inferred from direct assay
15647165 RGD
enables calmodulin binding IDA
IDA: Inferred from direct assay
16254000 RGD
enables cytoskeletal motor activity IDA
IDA: Inferred from direct assay
20080738 RGD
enables microfilament motor activity IDA
IDA: Inferred from direct assay
15647165 RGD
enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
IDA: Inferred from direct assay
20610386 RGD
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: Inferred from direct assay
20610386 RGD
Biological Process GO Annotation Evidence Reference Source
involved in actin filament bundle assembly IDA
IDA: Inferred from direct assay
15475577 RGD
involved in actin filament-based movement IDA
IDA: Inferred from direct assay
17298083 RGD
Cellular Component GO Annotation Evidence Reference Source
located in apical part of cell IDA
IDA: Inferred from direct assay
12486594 RGD
located in brush border IDA
IDA: Inferred from direct assay
11546671 RGD
located in cell periphery IDA
IDA: Inferred from direct assay
20610386 RGD
located in cytoplasm IDA
IDA: Inferred from direct assay
17298083 RGD
located in filopodium IDA
IDA: Inferred from direct assay
20610386 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
17298083 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

unconventional myosin-Ib

MMI-alpha

MMIa

myosin I alpha

myosin heavy chain myr 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08938 MYO1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myo1b NCBI NCBI:4430