Bex3 - brain expressed X-linked 3 Gene

Rattus norvegicus

Also known as Nade; Ngfrap1

Gene ID: 117089 | Gene type: protein coding

About Bex3

Summary

Enables nerve growth factor receptor binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within extrinsic apoptotic signaling pathway via death domain receptors. Located in cytoplasm. Biomarker of glaucoma; transient cerebral ischemia; and visual epilepsy. Orthologous to human BEX3 (brain expressed X-linked 3). [provided by Alliance of Genome Resources, Apr 2022]

Bex3 Products(4)

mRNA	Protein	Name
NM_001398797.1	NP_001385726.1	protein BEX3 isoform 2
NM_053401.3	NP_445853.1	protein BEX3 isoform 1
NM_001398797.1	NP_001385726.1	protein BEX3 isoform 2
NM_053401.3	NP_445853.1	protein BEX3 isoform 1

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables nerve growth factor receptor binding	IDA IDA: Inferred from direct assay	10764727	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	17355907	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	15958283	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

protein BEX3

brain-expressed X-linked protein 3 homolog	nerve growth factor receptor (TNFRSF16) associated protein 1
nerve growth factor receptor-associated protein 1	p75NTR-associated cell death executor
rBex3

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01482	BEX3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Bex3	NCBI	NCBI:27018

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