Bex3 - brain expressed X-linked 3 Gene

Also Known as Nade; Ngfrap1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117089

Summary

Enables nerve growth factor receptor binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within extrinsic apoptotic signaling pathway via death domain receptors. Located in cytoplasm. Biomarker of glaucoma; transient cerebral ischemia; and visual epilepsy. Orthologous to human BEX3 (brain expressed X-linked 3). [provided by Alliance of Genome Resources, Apr 2022]

Bex3 Products (4)

mRNA Protein Name
NM_001398797.1 NP_001385726.1 protein BEX3 isoform 2
NM_053401.3 NP_445853.1 protein BEX3 isoform 1
NM_001398797.1 NP_001385726.1 protein BEX3 isoform 2
NM_053401.3 NP_445853.1 protein BEX3 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables nerve growth factor receptor binding IDA
IDA: Inferred from direct assay
10764727 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
17355907 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15958283 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein BEX3

  • brain-expressed X-linked protein 3 homolog

  • nerve growth factor receptor (TNFRSF16) associated protein 1

  • nerve growth factor receptor-associated protein 1

  • p75NTR-associated cell death executor

  • rBex3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01482 BEX3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bex3 NCBI NCBI:27018