Kcnb2 - potassium voltage-gated channel subfamily B member 2 Gene

Rattus norvegicus

Also known as Kv2.2

Gene ID: 117105 | Gene type: protein coding

About Kcnb2

Summary

Enables delayed rectifier Potassium Channel activity; protein heterodimerization activity; and transmembrane transporter binding activity. Involved in potassium ion transmembrane transport and protein localization to plasma membrane. Located in dendrite and neuronal cell body membrane. Part of voltage-gated Potassium Channel complex. Orthologous to human KCNB2 (potassium voltage-gated channel subfamily B member 2). [provided by Alliance of Genome Resources, Apr 2022]

Kcnb2 Products(1)

mRNA	Protein	Name
NM_054000.2	NP_446452.2	potassium voltage-gated channel subfamily B member 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables delayed rectifier potassium channel activity	IDA IDA: Inferred from direct assay	1550672	RGD
enables protein heterodimerization activity	IDA IDA: Inferred from direct assay	20202934	RGD
enables transmembrane transporter binding	IPI IPI: Inferred from physical interaction	20202934	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in potassium ion transmembrane transport	IDA IDA: Inferred from direct assay	20202934	RGD
involved in potassium ion transport	IDA IDA: Inferred from direct assay	9305895	RGD
involved in protein localization to plasma membrane	IDA IDA: Inferred from direct assay	9305895	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in dendrite	IDA IDA: Inferred from direct assay	20202934	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	8463836	RGD
located in neuronal cell body membrane	IDA IDA: Inferred from direct assay	20202934	RGD
located in plasma membrane	IDA IDA: Inferred from direct assay	9305895	RGD
part of voltage-gated potassium channel complex	IDA IDA: Inferred from direct assay	9305895	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

potassium voltage-gated channel subfamily B member 2

CDRK	potassium channel, voltage gated Shab-related subfamily B, member 2
potassium voltage gated channel, Shab-related subfamily, member 2	voltage-gated potassium channel subunit Kv2.2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07107	KCNB2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Kcnb2	NCBI	NCBI:9312

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