Anxa5 - annexin A5 Gene

Also Known as Anx5; CPB-I

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11747

Summary

Predicted to enable several functions, including P-type calcium transporter activity; calcium-dependent phospholipid binding activity; and receptor tyrosine kinase binding activity. Acts upstream of or within response to organic substance. Located in endothelial microparticle and external side of plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; embryo mesenchyme; and genitourinary system. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system; myocardial infarction; and systemic scleroderma. Orthologous to human ANXA5 (annexin A5). [provided by Alliance of Genome Resources, Apr 2022]

Anxa5 Products (1)

mRNA Protein Name
NM_009673.2 NP_033803.1 annexin A5

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phosphatidylserine binding IDA
IDA: Inferred from direct assay
12000961 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14651927 MGI
Cellular Component GO Annotation Evidence References Source
located in endothelial microparticle IDA
IDA: Inferred from direct assay
20978343 MGI
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
17082577 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

annexin A5

  • CBP-I

  • PAP-I

  • PP4

  • VAC-alpha

  • anchorin CII

  • annexin V

  • annexin-5

  • calphobindin I

  • endonexin II

  • lipocortin V

  • placental anticoagulant protein 4

  • placental anticoagulant protein I

  • thromboplastin inhibitor

  • vascular anticoagulant-alpha

Anxa5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Anxa5 P48036 Kcnma1 Mus musculus Q08460
Confocal
19423573
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00765 ANXA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17223 Anxa5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23676 Anxa5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Anxa5 NCBI NCBI:308