Anxa6 - annexin A6 Gene

Also Known as Anx6; Cabm; Camb; AnxVI

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11749

Summary

Predicted to enable several functions, including GTP binding activity; ion channel activity; and phospholipid binding activity. Involved in apoptotic signaling pathway and mitochondrial calcium ion homeostasis. Acts upstream of or within calcium ion transport and regulation of muscle contraction. Located in perinuclear region of cytoplasm. Is expressed in blood vessel endothelium; dorsal aorta; primary palate; and yolk sac blood vessel. Orthologous to human ANXA6 (annexin A6). [provided by Alliance of Genome Resources, Apr 2022]

Anxa6 Products (2)

mRNA Protein Name
NM_001110211.2 NP_001103681.1 annexin A6 isoform b
NM_013472.5 NP_038500.2 annexin A6 isoform a

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
23341998 MGI
acts upstream of or within calcium ion transport IMP
IMP: Inferred from mutant phenotype
11919174 MGI
involved in mitochondrial calcium ion homeostasis IMP
IMP: Inferred from mutant phenotype
23341998 MGI
acts upstream of or within regulation of muscle contraction IMP
IMP: Inferred from mutant phenotype
11919174 MGI
Cellular Component GO Annotation Evidence References Source
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
15078881 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

annexin A6

  • 67 kDa calelectrin

  • CPB-II

  • annexin VI, p68

  • annexin-6

  • calphobindin-II

  • chromobindin-20

  • lipocortin VI

  • p68

  • p70

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS24635 Anxa6 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Anxa6 NCBI NCBI:309