St8sia2 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 Gene

Also Known as STX; Siat8b; SIAT8-B

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117523

Summary

Enables Sialyltransferase activity. Involved in several processes, including neuron projection extension; positive regulation of synapse assembly; and response to cocaine. Located in perinuclear region of cytoplasm and plasma membrane. Orthologous to human ST8SIA2 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

St8sia2 Products (1)

mRNA Protein Name
NM_057156.2 NP_476497.1 alpha-2,8-sialyltransferase 8B precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables sialyltransferase activity IMP
IMP: Inferred from mutant phenotype
16887122 RGD
Biological Process GO Annotation Evidence References Source
involved in neuron differentiation IEP
IEP: Inferred from expression pattern
8703013 RGD
involved in neuron projection extension IMP
IMP: Inferred from mutant phenotype
16887122 RGD
involved in positive regulation of neuron apoptotic process IDA
IDA: Inferred from direct assay
14635225 RGD
involved in positive regulation of synapse assembly IMP
IMP: Inferred from mutant phenotype
16887122 RGD
involved in response to cocaine IEP
IEP: Inferred from expression pattern
21536109 RGD
Cellular Component GO Annotation Evidence References Source
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
14635225 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-2,8-sialyltransferase 8B

  • ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 2

  • ST8Sia II

  • ST8SiaII

  • sialyltransferase 8 (alpha-2, 8-sialyltransferase) B

  • sialyltransferase 8 (alpha-2, 8-sialytransferase) B

  • sialyltransferase 8B

  • sialyltransferase St8Sia II

  • sialyltransfera

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13857 ST8SIA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens St8sia2 NCBI NCBI:8128