Slc4a7 - solute carrier family 4 member 7 Gene

Also Known as NBC3; NBCn1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117955

Summary

Predicted to enable sodium:bicarbonate symporter activity. Predicted to be involved in several processes, including auditory receptor cell development; bicarbonate transport; and regulation of intracellular pH. Predicted to act upstream of or within cochlear nucleus development; eye development; and visual perception. Located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and stereocilium. Orthologous to human SLC4A7 (solute carrier family 4 member 7). [provided by Alliance of Genome Resources, Apr 2022]

Slc4a7 Products (5)

mRNA Protein Name
NM_001270860.2 NP_001257789.1 sodium bicarbonate cotransporter 3 isoform 2
NM_001270861.2 NP_001257790.1 sodium bicarbonate cotransporter 3 isoform 3
NM_001413732.1 NP_001400661.1 sodium bicarbonate cotransporter 3 isoform 4
NM_001413733.1 NP_001400662.1 sodium bicarbonate cotransporter 3 isoform 5
NM_058211.3 NP_478118.1 sodium bicarbonate cotransporter 3 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
29743600 RGD
enables sodium:bicarbonate symporter activity IDA
IDA: Inferred from direct assay
10850716 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
10662737 RGD
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
10662737 RGD
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
16144965 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
15718246 RGD
located in stereocilium IDA
IDA: Inferred from direct assay
16301216 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium bicarbonate cotransporter 3

  • NBC-like protein

  • electroneutral sodium bicarbonate cotransporter 1

  • solute carrier family 4 sodium bicarbonate cotransporter member 7 variant NBCn1-G

  • solute carrier family 4 sodium bicarbonate cotransporter member 7 variant NBCn1-I

  • solute carrier famil

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS13272 SLC4A7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21936 Slc4a7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28452 Slc4a7 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc4a7 NCBI NCBI:9497