Arhgap6 - Rho GTPase activating protein 6 Gene

Also Known as RhoGAPX-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11856

Summary

Enables GTPase activator activity. Involved in positive regulation of GTPase activity. Acts upstream of or within actin filament organization; focal adhesion assembly; and regulation of GTPase activity. Located in actin Cytoskeleton. Used to study microphthalmia. Orthologous to human ARHGAP6 (Rho GTPase activating protein 6). [provided by Alliance of Genome Resources, Apr 2022]

Arhgap6 Products (6)

mRNA Protein Name
NM_001287530.1 NP_001274459.1 rho GTPase-activating protein 6 isoform c
NM_009707.4 NP_033837.2 rho GTPase-activating protein 6 isoform a
NM_178754.3 NP_848869.1 rho GTPase-activating protein 6 isoform b
NM_001287530.1 NP_001274459.1 rho GTPase-activating protein 6 isoform c
NM_009707.4 NP_033837.2 rho GTPase-activating protein 6 isoform a
NM_178754.3 NP_848869.1 rho GTPase-activating protein 6 isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
10699171 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin filament organization IDA
IDA: Inferred from direct assay
10699171 MGI
acts upstream of or within focal adhesion assembly IDA
IDA: Inferred from direct assay
10699171 MGI
involved in positive regulation of GTPase activity IDA
IDA: Inferred from direct assay
10699171 MGI
acts upstream of or within regulation of GTPase activity IDA
IDA: Inferred from direct assay
10699171 MGI
Cellular Component GO Annotation Evidence References Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
10699171 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho GTPase-activating protein 6

  • rho-type GTPase-activating protein 6

  • rho-type GTPase-activating protein RhoGAPX-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00940 ARHGAP6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgap6 NCBI NCBI:395