Arnt2 - aryl hydrocarbon receptor nuclear translocator 2 Gene

Also Known as Hif-2b; bHLHe1; mKIAA0307

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11864

Summary

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; Aryl Hydrocarbon Receptor binding activity; and protein heterodimerization activity. Involved in central nervous system development and positive regulation of transcription, DNA-templated. Acts upstream of or within in utero embryonic development and positive regulation of transcription by RNA polymerase II. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human ARNT2 (Aryl Hydrocarbon Receptor nuclear translocator 2). [provided by Alliance of Genome Resources, Apr 2022]

Arnt2 Products (7)

mRNA Protein Name
NM_001411920.1 NP_001398849.1 aryl hydrocarbon receptor nuclear translocator 2 isoform b
NM_001411921.1 NP_001398850.1 aryl hydrocarbon receptor nuclear translocator 2 isoform c
NM_001411922.1 NP_001398851.1 aryl hydrocarbon receptor nuclear translocator 2 isoform c
NM_001411923.1 NP_001398852.1 aryl hydrocarbon receptor nuclear translocator 2 isoform c
NM_001411924.1 NP_001398853.1 aryl hydrocarbon receptor nuclear translocator 2 isoform d
NM_001411925.1 NP_001398854.1 aryl hydrocarbon receptor nuclear translocator 2 isoform e
NM_007488.4 NP_031514.3 aryl hydrocarbon receptor nuclear translocator 2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
8657146 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
8657146 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
8657146 MGI
enables aryl hydrocarbon receptor binding IPI
IPI: Inferred from physical interaction
8657146 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
27782878 MGI
enables protein heterodimerization activity IDA
IDA: Inferred from direct assay
27782878 MGI
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
8927054 MGI
Biological Process GO Annotation Evidence References Source
involved in central nervous system development IMP
IMP: Inferred from mutant phenotype
11318878 MGI
involved in in utero embryonic development IEP
IEP: Inferred from expression pattern
12502753 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
8657146 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
14701734 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
8657146 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
14701734 MGI
Cellular Component GO Annotation Evidence References Source
part of transcription regulator complex IDA
IDA: Inferred from direct assay
14701734 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

aryl hydrocarbon receptor nuclear translocator 2

  • ARNT protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01012 ARNT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arnt2 NCBI NCBI:9915