Atp6v0d1 - ATPase, H+ transporting, lysosomal V0 subunit D1 Gene

Mus musculus

Also known as P39; Ac39; VATX; Vma6; Atp6d

Gene ID: 11972 | Gene type: protein coding

About Atp6v0d1

Summary

Contributes to proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in cellular cation homeostasis; cellular response to increased oxygen levels; and vacuolar transport. Predicted to act upstream of or within cell projection organization and ion transport. Located in early endosome. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; nervous system; and sensory organ. Orthologous to human ATP6V0D1 (ATPase H+ transporting V0 subunit d1). [provided by Alliance of Genome Resources, Apr 2022]

Atp6v0d1 Products(1)

mRNA	Protein	Name
NM_013477.4	NP_038505.2	V-type proton ATPase subunit d 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	29644770	MGI
contributes to proton-transporting ATPase activity, rotational mechanism	IDA IDA: Inferred from direct assay	12527205	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in synaptic vesicle lumen acidification	EXP EXP: Inferred from Experiment	28793259	MGI
involved in synaptic vesicle lumen acidification	IDA IDA: Inferred from direct assay	28793259	MGI
involved in synaptic vesicle lumen acidification	IMP IMP: Inferred from mutant phenotype	28793259	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in early endosome	IDA IDA: Inferred from direct assay	9670047	MGI
part of proton-transporting V-type ATPase complex	IDA IDA: Inferred from direct assay	12963731	MGI
part of proton-transporting V-type ATPase, V0 domain	IDA IDA: Inferred from direct assay	12963731	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

V-type proton ATPase subunit d 1

ATPase, H+ transporting, V0 subunit D	ATPase, H+ transporting, lysosomal (vacuolar proton pump), 42 kDa
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit D	V-ATPase 40 kDa accessory protein
V-ATPase AC39 subunit	V-ATPase subunit d 1
lysosomal 38k

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01221	ATP6V0D1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Atp6v0d1	NCBI	NCBI:9114

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