Slc7a2 - solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 Gene

Also Known as Tea; 20.5; Cat2; Atrc2; CAT-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11988

Summary

Enables L-amino acid transmembrane transporter activity. Involved in regulation of macrophage activation. Acts upstream of or within several processes, including L-alpha-amino acid transmembrane transport; nitric oxide biosynthetic process; and nitric oxide production involved in inflammatory response. Is integral component of membrane. Is expressed in several structures, including alimentary system; bone; brain; genitourinary system; and respiratory system. Orthologous to human SLC7A2 (solute carrier family 7 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc7a2 Products (2)

mRNA Protein Name
NM_001044740.2 NP_001038205.1 cationic amino acid transporter 2 isoform 2
NM_007514.3 NP_031540.2 cationic amino acid transporter 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables L-arginine transmembrane transporter activity IDA
IDA: Inferred from direct assay
9174363 MGI
enables L-arginine transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
11278602 MGI
Biological Process GO Annotation Evidence References Source
involved in L-arginine transmembrane transport IDA
IDA: Inferred from direct assay
9174363 MGI
acts upstream of or within L-arginine transmembrane transport IMP
IMP: Inferred from mutant phenotype
11278602 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
11278602 MGI
acts upstream of or within macrophage activation IMP
IMP: Inferred from mutant phenotype
16703566 MGI
acts upstream of or within nitric oxide biosynthetic process IMP
IMP: Inferred from mutant phenotype
12675924 MGI
acts upstream of or within nitric oxide production involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
11278602 MGI
acts upstream of or within regulation of inflammatory response IMP
IMP: Inferred from mutant phenotype
17003120 MGI
involved in regulation of macrophage activation IMP
IMP: Inferred from mutant phenotype
16670299 MGI
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
8187816 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cationic amino acid transporter 2

  • T-cell early activation protein

  • amino acid transporter, cationic 2 (low affinity)

  • cationic amino acid transporter 2A

  • cationic amino acid transporter 2B

  • low affinity cationic amino acid transporter 2

  • solute carrier family 7 member 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS21940 Slc7a2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13328 SLC7A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28457 Slc7a2 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc7a2 NCBI NCBI:6542