Bex3 - brain expressed X-linked 3 Gene

Also Known as Nade; Gcap27; Ngfrap1; DXWsu67e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12070

Summary

Enables death receptor binding activity. Acts upstream of or within extrinsic apoptotic signaling pathway via death domain receptors. Located in cytosol. Is expressed in embryo; extraembryonic component; pelvic ganglion; and urethra of female. Orthologous to human BEX3 (brain expressed X-linked 3). [provided by Alliance of Genome Resources, Apr 2022]

Bex3 Products (3)

mRNA Protein Name
NM_001110233.1 NP_001103703.1 protein BEX3 isoform a
NM_001110234.1 NP_001103704.1 protein BEX3 isoform b
NM_009750.2 NP_033880.1 protein BEX3 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables death receptor binding IPI
IPI: Inferred from physical interaction
10764727 MGI
enables molecular function inhibitor activity IDA
IDA: Inferred from direct assay
34562363 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within extrinsic apoptotic signaling pathway via death domain receptors IPI
IPI: Inferred from physical interaction
10764727 MGI
involved in negative regulation of protein ubiquitination IDA
IDA: Inferred from direct assay
34562363 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
10764727 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein BEX3

  • brain-expressed X-linked protein 3 homolog

  • granule cell antiserum positive 27

  • nerve growth factor receptor (TNFRSF16) associated protein 1

  • nerve growth factor receptor-associated protein 1

  • p75NTR-associated Cell Death Executor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01482 BEX3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bex3 NCBI NCBI:27018