2. Gene
  3. Bfsp1 - beaded filament structural protein 1, in lens-CP94 Gene

Bfsp1 - beaded filament structural protein 1, in lens-CP94 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CP95

Gene ID: 12075 | Gene type: protein coding

About Bfsp1

Summary

A structural constituent of eye lens. Involved in intermediate filament organization. Acts upstream of or within cell maturation and lens fiber cell development. Located in cytoplasm; intermediate filament; and plasma membrane. Is expressed in several structures, including eye and male reproductive gland or organ. Human ortholog(s) of this gene implicated in cataract 33. Orthologous to human BFSP1 (beaded filament structural protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Bfsp1 Products(2)

mRNA Protein Name
NM_001291061.1 NP_001277990.1 filensin isoform a
NM_009751.2 NP_033881.2 filensin isoform b
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19029034 MGI
enables structural constituent of eye lens IDA
IDA: Inferred from direct assay
15037121 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cell maturation IMP
IMP: Inferred from mutant phenotype
18326727 MGI
involved in intermediate filament organization IMP
IMP: Inferred from mutant phenotype
27559293 MGI
acts upstream of or within lens fiber cell development IDA
IDA: Inferred from direct assay
15037121 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12835653 MGI
located in intermediate filament IDA
IDA: Inferred from direct assay
15037121 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
19029034 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

filensin

beaded filament structural protein in lens-CP94

lens fiber cell beaded-filament structural protein CP 95

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01486 BFSP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bfsp1 NCBI NCBI:631