Bsn - bassoon Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12217

Summary

A structural constituent of presynaptic active zone. Involved in presynapse to nucleus signaling pathway; protein localization to synapse; and regulation of synaptic vesicle cycle. Located in several cellular components, including glutamatergic synapse; postsynaptic density; and presynaptic active zone cytoplasmic component. Is active in GABA-ergic synapse and Schaffer collateral - CA1 synapse. Is expressed in nervous system and retina. Used to study epilepsy. Orthologous to human BSN (bassoon presynaptic cytomatrix protein). [provided by Alliance of Genome Resources, Apr 2022]

Bsn Products (1)

mRNA Protein Name
NM_007567.2 NP_031593.2 protein bassoon

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17869247 MGI
enables structural constituent of presynaptic active zone IDA
IDA: Inferred from direct assay
21092861 MGI
enables structural constituent of presynaptic active zone IMP
IMP: Inferred from mutant phenotype
21092861 MGI
Biological Process GO Annotation Evidence References Source
involved in protein localization to synapse IGI
IGI: Inferred from genetic interaction
25652077 MGI
involved in regulation of synaptic vesicle cycle IDA
IDA: Inferred from direct assay
21092860 MGI
involved in regulation of synaptic vesicle cycle IMP
IMP: Inferred from mutant phenotype
21092860 MGI
involved in synaptic vesicle clustering IDA
IDA: Inferred from direct assay
20332206 MGI
involved in synaptic vesicle clustering IMP
IMP: Inferred from mutant phenotype
20332206 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
26793095 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
26793095 MGI
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
26793095 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
26793095 MGI
located in axon IDA
IDA: Inferred from direct assay
23791195 MGI
located in cell surface IDA
IDA: Inferred from direct assay
21940441 MGI
is active in cochlear hair cell ribbon synapse IDA
IDA: Inferred from direct assay
21092861 MGI
is active in cochlear hair cell ribbon synapse IMP
IMP: Inferred from mutant phenotype
21092861 MGI
located in dendrite IDA
IDA: Inferred from direct assay
21940441 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
21092860 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
21092860 MGI
located in neuron projection terminus IDA
IDA: Inferred from direct assay
12115694 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
17114649 MGI
located in presynapse IDA
IDA: Inferred from direct assay
24554721 MGI
located in presynaptic active zone IDA
IDA: Inferred from direct assay
15935055 MGI
located in synapse IDA
IDA: Inferred from direct assay
10900017 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein bassoon

  • presynaptic cytomatrix protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-114591 Spiromesifen Inhibitor 99.42% Unkown
HY-114591S Spiromesifen-d9 / Unkown
HY-RS01644 BSN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bsn NCBI NCBI:8927