Capza1 - capping actin protein of muscle Z-line subunit alpha 1 Gene

Also Known as CAPZ; CAZ1; Cappa1; capZ alpha-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12340

Summary

Contributes to actin filament binding activity. Acts upstream of or within barbed-end actin filament capping. Located in several cellular components, including brush border; cell-cell junction; and cortical Cytoskeleton. Part of F-actin capping protein complex. Is expressed in early conceptus; head mesenchyme; and lung. Orthologous to human CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Capza1 Products (2)

mRNA Protein Name
NM_001355044.1 NP_001341973.1 F-actin-capping protein subunit alpha-1 isoform 2
NM_009797.3 NP_033927.2 F-actin-capping protein subunit alpha-1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to actin filament binding IDA
IDA: Inferred from direct assay
17656356 MGI
contributes to protein binding IPI
IPI: Inferred from physical interaction
11604420 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
23793062 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within barbed-end actin filament capping IDA
IDA: Inferred from direct assay
17656356 MGI
Cellular Component GO Annotation Evidence References Source
part of F-actin capping protein complex IDA
IDA: Inferred from direct assay
11604420 MGI
located in brush border IDA
IDA: Inferred from direct assay
22114352 MGI
located in cell-cell junction IDA
IDA: Inferred from direct assay
23793062 MGI
located in cortical cytoskeleton IDA
IDA: Inferred from direct assay
18723693 MGI
located in membrane IDA
IDA: Inferred from direct assay
18723693 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-actin-capping protein subunit alpha-1

  • F-actin capping protein alpha-1 subunit

  • capping protein (actin filament) muscle Z-line, alpha 1

  • capping protein alpha 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01902 CAPZA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29162 Mov10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Capza1 NCBI NCBI:829