Runx1t1 - RUNX1 translocation partner 1 Gene

Also Known as ETO; MTG8; Cbfa2t1h

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12395

Summary

Enables identical protein binding activity. Involved in negative regulation of fat cell differentiation. Acts upstream of or within fat cell differentiation; regulation of DNA binding activity; and regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human RUNX1T1 (RUNX1 partner transcriptional co-repressor 1). [provided by Alliance of Genome Resources, Apr 2022]

Runx1t1 Products (3)

mRNA Protein Name
NM_001111026.2 NP_001104496.1 protein CBFA2T1 isoform 2
NM_001111027.2 NP_001104497.1 protein CBFA2T1 isoform 1
NM_009822.3 NP_033952.1 protein CBFA2T1 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
NOT enables DNA binding IDA
IDA: Inferred from direct assay
15509789 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
15509789 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15509789 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within fat cell differentiation IDA
IDA: Inferred from direct assay
15509789 MGI
involved in negative regulation of fat cell differentiation IMP
IMP: Inferred from mutant phenotype
26774823 MGI
acts upstream of or within regulation of DNA binding IDA
IDA: Inferred from direct assay
15509789 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
15509789 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
15509789 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein CBFA2T1

  • CBFA2T1 identified gene homolog

  • acute myelogenous leukemia 1 translocation 1 protein

  • runt-related transcription factor 1

  • translocated to, 1 (cyclin D-related)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12350 RUNX1T1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Runx1t1 NCBI NCBI:862