2. Gene
  3. Cbfa2t2 - CBFA2/RUNX1 translocation partner 2 Gene

Cbfa2t2 - CBFA2/RUNX1 translocation partner 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MTGR1; Cbfa2t2h; A430091M07; C330013D05Rik

Gene ID: 12396 | Gene type: protein coding

About Cbfa2t2

Summary

Enables transcription corepressor activity. Involved in intestinal epithelial cell differentiation and negative regulation of Notch signaling pathway. Acts upstream of or within epithelial cell differentiation and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; blastocyst; brain; genitourinary system; and sensory organ. Orthologous to human CBFA2T2 (CBFA2/RUNX1 partner transcriptional co-repressor 2). [provided by Alliance of Genome Resources, Apr 2022]

Cbfa2t2 Products(3)

mRNA Protein Name
NM_001285446.1 NP_001272375.1 protein CBFA2T2 isoform 3
NM_009823.1 NP_033953.1 protein CBFA2T2 isoform 2
NM_172860.2 NP_766448.1 protein CBFA2T2 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16227606 MGI
enables transcription corepressor activity IDA
IDA: Inferred from direct assay
16227606 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
16227606 MGI
involved in intestinal epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
25398765 MGI
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
16227606 MGI
involved in negative regulation of Notch signaling pathway IMP
IMP: Inferred from mutant phenotype
25398765 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
19799863 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein CBFA2T2

CBFA2T2 identified gene homolog

MTG8-like protein

MTG8-related protein 1

core-binding factor, runt domain, alpha subunit 2, translocated to, 2 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01993 CBFA2T2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cbfa2t2 NCBI NCBI:9139