Cbx1 - chromobox 1 Gene

Also Known as Cbx; M31; HP1B; MOD1; Cbx-rs2; Hp1beta; E430007M08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12412

Summary

Enables identical protein binding activity. Acts upstream of or within negative regulation of transcription, DNA-templated. Located in chromocenter; pericentric heterochromatin; and pronucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human CBX1 (chromobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Cbx1 Products (5)

mRNA Protein Name
NM_001362560.1 NP_001349489.1 chromobox protein homolog 1 isoform 1
NM_001362561.1 NP_001349490.1 chromobox protein homolog 1 isoform 1
NM_001362563.1 NP_001349492.1 chromobox protein homolog 1 isoform 1
NM_001362564.1 NP_001349493.1 chromobox protein homolog 1 isoform 2
NM_007622.4 NP_031648.1 chromobox protein homolog 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
10747027 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8978696 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
10562550 MGI
Cellular Component GO Annotation Evidence References Source
located in chromatin IDA
IDA: Inferred from direct assay
16880268 MGI
located in chromocenter IDA
IDA: Inferred from direct assay
15322135 MGI
located in female pronucleus IDA
IDA: Inferred from direct assay
15922569 MGI
located in male pronucleus IDA
IDA: Inferred from direct assay
15922569 MGI
located in nucleus IDA
IDA: Inferred from direct assay
22770845 MGI
located in pericentric heterochromatin IDA
IDA: Inferred from direct assay
11980720 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chromobox protein homolog 1

  • chromobox homolog 1

  • heterochromatin protein 1 homolog beta

  • heterochromatin protein p25

  • modifier 1 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-181089 CBX2-IN-1 Inhibitor / Unkown
HY-RS02008 CBX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cbx1 NCBI NCBI:10951