Cct5 - chaperonin containing Tcp1, subunit 5 (epsilon) Gene

Also Known as Ccte; TCPE; mKIAA0098; CCT-epsilon; TCP-1-epsilon

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12465

Summary

Predicted to enable several functions, including G-protein beta-subunit binding activity; beta-tubulin binding activity; and mRNA binding activity. Acts upstream of or within binding activity of sperm to zona pellucida and toxin transport. Located in cell body. Part of chaperonin-containing T-complex and zona pellucida receptor complex. Is expressed in 1st branchial arch mandibular component and mandible primordium. Orthologous to human CCT5 (chaperonin containing TCP1 subunit 5). [provided by Alliance of Genome Resources, Apr 2022]

Cct5 Products (2)

mRNA Protein Name
NM_001348035.1 NP_001334964.1 T-complex protein 1 subunit epsilon isoform 2
NM_007637.3 NP_031663.1 T-complex protein 1 subunit epsilon isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10747865 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within binding of sperm to zona pellucida IDA
IDA: Inferred from direct assay
21880732 MGI
Cellular Component GO Annotation Evidence References Source
located in cell body IDA
IDA: Inferred from direct assay
21880732 MGI
part of chaperonin-containing T-complex IDA
IDA: Inferred from direct assay
7828721 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

T-complex protein 1 subunit epsilon

Cct5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Cct5 P80316 Spmap2 Mus musculus Q9JMB1
Y2H
10747865
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13685 Miltefosine Inhibitor 99.92% Yes

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13685S1 Miltefosine-d4 Inhibitor / Unkown
HY-RS02182 CCT5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cct5 NCBI NCBI:22948