Arhgap31 - Rho GTPase activating protein 31 Gene

Also Known as Cdgap; 5830477L08Rik; D330026I07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12549

Summary

Enables GTPase activator activity and SH3 domain binding activity. Acts upstream of or within small GTPase mediated signal transduction. Located in lamellipodium. Is expressed in several structures, including 1st branchial arch; central nervous system; heart; retina layer; and surface ectoderm. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome. Orthologous to human ARHGAP31 (Rho GTPase activating protein 31). [provided by Alliance of Genome Resources, Apr 2022]

Arhgap31 Products (1)

mRNA Protein Name
NM_020260.2 NP_064656.2 rho GTPase-activating protein 31

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
11744688 MGI
enables SH3 domain binding IDA
IDA: Inferred from direct assay
11744688 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11744688 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within small GTPase-mediated signal transduction IDA
IDA: Inferred from direct assay
11744688 MGI
Cellular Component GO Annotation Evidence References Source
located in lamellipodium IDA
IDA: Inferred from direct assay
11744688 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho GTPase-activating protein 31

  • CDC42 GTPase-activating protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00930 ARHGAP31 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgap31 NCBI NCBI:57514