Cdh11 - cadherin 11 Gene

Also Known as Cad11; OSF-4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12552

Summary

This gene encodes a type II classical Cadherin and preproprotein that is proteolytically processed to generate a mature protein product. This protein product is an integral membrane protein that mediates calcium-dependent cell-cell adhesion, specifically in the context of bone development. Homozygous knockout mice for this gene exhibit impaired synovium development and reduced bone density. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015]

Cdh11 Products (1)

mRNA Protein Name
NM_009866.5 NP_033996.4 cadherin-11 preproprotein

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within corticospinal tract morphogenesis IGI
IGI: Inferred from genetic interaction
22284184 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
10860580 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
10860580 MGI
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
10860580 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
10860580 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
12139922 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
10860580 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12139922 MGI
is active in synapse IDA
IDA: Inferred from direct assay
10860580 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cadherin-11

  • OB-cadherin

  • osteoblast cadherin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-177575 CDH11-IN-1 Inhibitor 99.66% Unkown
HY-RS02322 CDH11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19993 Cdh11 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26497 Cdh11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdh11 NCBI NCBI:1009