2. Gene
  3. Ces1g - carboxylesterase 1G Gene

Ces1g - carboxylesterase 1G Gene

  • Gene
  • Protein
  • Agent
Mus musculus

Also known as CEH; Ces1; Ces-1; Ses-1

Gene ID: 12623 | Gene type: protein coding

About Ces1g

Summary

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and Cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. The expression and activity of this gene is age-related but independent of growth hormone level. This gene is clustered with Ces7 and Ces3 on chromosome 8. [provided by RefSeq, Jun 2010]

Ces1g Products(1)

mRNA Protein Name
NM_021456.4 NP_067431.2 liver carboxylesterase 1 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within chylomicron assembly IMP
IMP: Inferred from mutant phenotype
23145182 MGI
acts upstream of or within regulation of chylomicron remnant clearance IMP
IMP: Inferred from mutant phenotype
23145182 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
23145182 MGI
acts upstream of or within regulation of triglyceride metabolic process IMP
IMP: Inferred from mutant phenotype
23145182 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

liver carboxylesterase 1

ES-x

acyl-coenzyme A:cholesterol acyltransferase

carboxylesterase 1

cholesteryl ester hydrolase

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-E70600 Human CES1 Enzyme / Unkown
HY-RS02543 CES1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown