2. Gene
  3. Col17a1 - collagen, type XVII, alpha 1 Gene

Col17a1 - collagen, type XVII, alpha 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Bpag; BP180; Bpag2

Gene ID: 12821 | Gene type: protein coding

About Col17a1

Summary

Predicted to be an extracellular matrix structural constituent. Predicted to be involved in extracellular matrix organization and hemidesmosome assembly. Located in hemidesmosome. Is expressed in several structures, including esophagus; genitourinary system; oral epithelium; sensory organ; and skin. Used to study bullous pemphigoid and junctional epidermolysis bullosa non-Herlitz type. Human ortholog(s) of this gene implicated in epithelial recurrent erosion dystrophy; junctional epidermolysis bullosa; and junctional epidermolysis bullosa non-Herlitz type. Orthologous to human COL17A1 (Collagen type XVII alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2022]

Col17a1 Products(2)

mRNA Protein Name
NM_001290825.1 NP_001277754.1 collagen alpha-1(XVII) chain isoform 1
NM_007732.2 NP_031758.2 collagen alpha-1(XVII) chain isoform 2
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21979170 MGI
Cellular Component GO Annotation Evidence Reference Source
located in hemidesmosome IDA
IDA: Inferred from direct assay
8707838 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

collagen alpha-1(XVII) chain

180 kDa bullous pemphigoid antigen 2

bullous pemphigoid antigen 2

procollagen, type XVII, alpha 1

Col17a1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Col17a1 Q07563 ELANE Homo sapiens P08246
Protease Assay
21979170
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15898 Y-320 99.03% Unkown
HY-RS02967 COL17A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Col17a1 NCBI NCBI:1308