Cpa3 - carboxypeptidase A3, mast cell Gene

Also Known as MC-CPA

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12873

Summary

This gene encodes a member of the Carboxypeptidase A family of zinc metalloproteases and preproprotein that is proteolytically processed to generate a mature protein product. This product is released by mast cells and may be involved in the degradation of endogenous proteins and the inactivation of venom-associated peptides. Homozygous knockout mice for this gene exhibit impaired mast cell development. [provided by RefSeq, Aug 2015]

Cpa3 Products (1)

mRNA Protein Name
NM_007753.2 NP_031779.1 mast cell carboxypeptidase A preproprotein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables peptidase activity IDA
IDA: Inferred from direct assay
23624557 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of angiotensin levels in blood IGI
IGI: Inferred from genetic interaction
15173164 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mast cell carboxypeptidase A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-70005 CPA inhibitor 99.78% Unkown
HY-RS03082 CPA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03083 CPA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cpa3 NCBI NCBI:1359