Cpne6 - copine VI Gene
Species: Mus musculus
Summary
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encodes a calcium-dependent protein containing two N-terminal type II C2 domains and an Integrin A domain-like sequence in the C-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2018]
Cpne6 Products (8)
| mRNA | Protein | Name |
|---|---|---|
| NM_001136057.3 | NP_001129529.1 | copine-6 isoform a |
| NM_001146183.2 | NP_001139655.1 | copine-6 isoform b |
| NM_001360193.1 | NP_001347122.1 | copine-6 isoform a |
| NM_009947.4 | NP_034077.1 | copine-6 isoform a |
| NM_001136057.3 | NP_001129529.1 | copine-6 isoform a |
| NM_001146183.2 | NP_001139655.1 | copine-6 isoform b |
| NM_001360193.1 | NP_001347122.1 | copine-6 isoform a |
| NM_009947.4 | NP_034077.1 | copine-6 isoform a |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables phosphatidylserine binding |
IDA
IDA: Inferred from direct assay
|
9886090 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
10403379 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in cellular response to calcium ion |
IMP
IMP: Inferred from mutant phenotype
|
21087455 | MGI |
| involved in postsynaptic actin cytoskeleton organization |
EXP
EXP: Inferred from Experiment
|
27194588 | MGI |
| involved in postsynaptic actin cytoskeleton organization |
IDA
IDA: Inferred from direct assay
|
27194588 | MGI |
| involved in postsynaptic actin cytoskeleton organization |
IMP
IMP: Inferred from mutant phenotype
|
27194588 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in axon |
IDA
IDA: Inferred from direct assay
|
9886090 | MGI |
| located in clathrin-coated endocytic vesicle |
IDA
IDA: Inferred from direct assay
|
21087455 | MGI |
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
21087455 | MGI |
| located in dendrite |
IDA
IDA: Inferred from direct assay
|
9886090 | MGI |
| located in membrane |
IDA
IDA: Inferred from direct assay
|
9886090 | MGI |
| located in plasma membrane |
IDA
IDA: Inferred from direct assay
|
21087455 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
copine-6 |
|