Crygd - crystallin, gamma D Gene

Also Known as Aey4; Lop12; Cryg-1; DGcry-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12967

Summary

A structural constituent of eye lens. Acts upstream of or within lens fiber cell differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including sensory organ; skeleton; and tarsus. Used to study cataract 2 multiple types and cataract 4 multiple types. Human ortholog(s) of this gene implicated in cataract 4 multiple types and cataract 7. Orthologous to human CRYGD (crystallin gamma D). [provided by Alliance of Genome Resources, Apr 2022]

Crygd Products (1)

mRNA Protein Name
NM_007776.3 NP_031802.2 gamma-crystallin D

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables structural constituent of eye lens IDA
IDA: Inferred from direct assay
17652744 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within eye development IMP
IMP: Inferred from mutant phenotype
15037589 MGI
acts upstream of or within lens development in camera-type eye IMP
IMP: Inferred from mutant phenotype
10704279 MGI
acts upstream of or within lens fiber cell differentiation IMP
IMP: Inferred from mutant phenotype
17652744 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17652744 MGI
located in nucleus IDA
IDA: Inferred from direct assay
17652744 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-crystallin D

  • gamma-D-crystallin

  • gamma-crystallin 1

  • lens opacity 12

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03215 CRYGD Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crygd NCBI NCBI:1421