Crygs - crystallin, gamma S Gene

Also Known as Opj; rncat

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12970

Summary

A structural constituent of eye lens. Acts upstream of or within lens development in camera-type eye and morphogenesis of an epithelium. Is expressed in alimentary system; eye; and genitourinary system. Used to study cataract 20 multiple types. Human ortholog(s) of this gene implicated in cataract 20 multiple types. Orthologous to human CRYGS (crystallin gamma S). [provided by Alliance of Genome Resources, Apr 2022]

Crygs Products (1)

mRNA Protein Name
NM_009967.2 NP_034097.1 gamma-crystallin S

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables structural constituent of eye lens IMP
IMP: Inferred from mutant phenotype
12079281 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within lens development in camera-type eye IMP
IMP: Inferred from mutant phenotype
6877261 MGI
acts upstream of or within morphogenesis of an epithelium IMP
IMP: Inferred from mutant phenotype
12079281 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-crystallin S

  • beta-crystallin S

  • opacity due to poor secondary fiber cell junction

  • recessive nuclear cataract

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03216 CRYGS Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crygs NCBI NCBI:1427