Celf1 - CUGBP, Elav-like family member 1 Gene

Also Known as CUGBP; NAB50; CUG-BP; Cugbp1; HNAB50; Brunol2; CUG-BP1; D2Wsu101e; 1600010O03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13046

Summary

Enables long noncoding RNA binding activity; mRNA 5'-UTR binding activity; and translation initiation factor binding activity. Acts upstream of or within several processes, including forebrain development; mRNA splice site selection; and regulation of gene expression. Located in cytoplasm and nucleus. Is expressed in several structures, including branchial arch; early embryo; musculature; nervous system; and testis. Orthologous to human CELF1 (CUGBP Elav-like family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Celf1 Products (25)

mRNA Protein Name
NM_001244891.2 NP_001231820.1 CUGBP Elav-like family member 1 isoform 2
NM_001244903.2 NP_001231832.1 CUGBP Elav-like family member 1 isoform 2
NM_001406164.1 NP_001393093.1 CUGBP Elav-like family member 1 isoform 1
NM_001406165.1 NP_001393094.1 CUGBP Elav-like family member 1 isoform 1
NM_001406166.1 NP_001393095.1 CUGBP Elav-like family member 1 isoform 2
NM_001406167.1 NP_001393096.1 CUGBP Elav-like family member 1 isoform 2
NM_001406168.1 NP_001393097.1 CUGBP Elav-like family member 1 isoform 3
NM_001406169.1 NP_001393098.1 CUGBP Elav-like family member 1 isoform 4
NM_001406170.1 NP_001393099.1 CUGBP Elav-like family member 1 isoform 5
NM_001406171.1 NP_001393100.1 CUGBP Elav-like family member 1 isoform 5
NM_001406172.1 NP_001393101.1 CUGBP Elav-like family member 1 isoform 6
NM_001406173.1 NP_001393102.1 CUGBP Elav-like family member 1 isoform 6
NM_001406174.1 NP_001393103.1 CUGBP Elav-like family member 1 isoform 6
NM_001406175.1 NP_001393104.1 CUGBP Elav-like family member 1 isoform 6
NM_001406176.1 NP_001393105.1 CUGBP Elav-like family member 1 isoform 7
NM_001406177.1 NP_001393106.1 CUGBP Elav-like family member 1 isoform 8
NM_001406178.1 NP_001393107.1 CUGBP Elav-like family member 1 isoform 8
NM_001406179.1 NP_001393108.1 CUGBP Elav-like family member 1 isoform 9
NM_001406180.1 NP_001393109.1 CUGBP Elav-like family member 1 isoform 10
NM_001406181.1 NP_001393110.1 CUGBP Elav-like family member 1 isoform 11
NM_001406182.1 NP_001393111.1 CUGBP Elav-like family member 1 isoform 11
NM_001406183.1 NP_001393112.1 CUGBP Elav-like family member 1 isoform 12
NM_001406184.1 NP_001393113.1 CUGBP Elav-like family member 1 isoform 13
NM_017368.4 NP_059064.2 CUGBP Elav-like family member 1 isoform 1
NM_198683.3 NP_941955.1 CUGBP Elav-like family member 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables lncRNA binding IPI
IPI: Inferred from physical interaction
28763438 MGI
enables mRNA binding IDA
IDA: Inferred from direct assay
32245946 MGI
enables mRNA binding IPI
IPI: Inferred from physical interaction
28763438 MGI
enables translation initiation factor binding IDA
IDA: Inferred from direct assay
16931514 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cerebral cortex development IMP
IMP: Inferred from mutant phenotype
32245946 MGI
acts upstream of or within mRNA splice site recognition IDA
IDA: Inferred from direct assay
11158314 MGI
acts upstream of or within positive regulation of multicellular organism growth IMP
IMP: Inferred from mutant phenotype
17130239 MGI
acts upstream of or within regulation of alternative mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
32109384 MGI
acts upstream of or within regulation of alternative mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
32109384 MGI
acts upstream of or within spermatid development IMP
IMP: Inferred from mutant phenotype
17130239 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17130239 MGI
located in male germ cell nucleus IDA
IDA: Inferred from direct assay
17130239 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15830352 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CUGBP Elav-like family member 1

  • 50 kDa nuclear polyadenylated RNA-binding protein

  • CELF-1

  • CUG triplet repeat RNA-binding protein 1

  • CUG-BP- and ETR-3-like factor 1

  • EDEN-BP homolog

  • RNA-binding protein BRUNOL-2

  • brain protein F41

  • bruno-like protein 2

  • deadenylation factor CUG-BP

  • dead

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02459 CELF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22429 Celf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28952 Celf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Celf1 NCBI NCBI:10658