IL17RE - interleukin 17 receptor E Gene

Homo sapiens

Gene ID: 132014 | Gene type: protein coding

About IL17RE

Cytogenetic location: 3p25.3 Genomic coordinates (GRCh38): 3:9,902,093-9,916,402 (from NCBI)

This gene has 11 transcripts (splice variants), 180 orthologues and 4 paralogues. Broad expression in duodenum (RPKM 10.6), skin (RPKM 9.9) and 17 other tissues.

Summary

This gene encodes a transmembrane protein that functions as the receptor for interleukin-17C. The encoded protein signals to downstream components of the mitogen activated protein kinase (MAPK) pathway. Activity of this protein is important in the immune response to Bacterial pathogens. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013]

IL17RE Products(4)

mRNA	Protein	Name
NM_001193380.2	NP_001180309.1	interleukin-17 receptor E isoform 6 precursor
NM_153480.2	NP_705613.1	interleukin-17 receptor E isoform 1 precursor
NM_153481.2	NP_705614.1	interleukin-17 receptor E isoform 2
NM_153483.2	NP_705616.2	interleukin-17 receptor E isoform 5

IL17RE Protein Structure

IL17_R_N

SEFIR

0
200
400
600
667 a.a.

Protein Preferred Names

Protein Names

interleukin-17 receptor E

IL-17 receptor E

Recombinant IL17RE Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72576	IL-17RE Protein, Human (HEK293, Fc)	Q8NFR9 (T155-H454)	≥95%

Related Diseases

Diseases

Alias

Cutaneous Candidiasis

Candidiasis, Cutaneous

Seborrheic Infantile Dermatitis

Cradle Cap	Infantile Seborrhoeic Dermatitis
Seborrhoea Capitis	Seborrhoeic Dermatitis Of Scalp
Seborrhoeic Eczema Of Scalp	Complement 5 Dysfunction
Generalized Seborrheic Dermatitis Of Infants	Infantile Seborrheic Dermatitis
Pityriasis Capitis	Seborrhea Capitis
Seborrhea Sicca	Dandruff
Complement Component 5 Deficiency	Seborrheic Dermatitis
Seborrheic Dermatitis Of Scalp	Scurfiness Of Scalp
Seborrheic Dermatitis Of Infancy	Infantile Seborrhoeic Eczema
Neonatal Seborrhoeic Dermatitis	Infantile Seborrhoeic Dermatitis Of The Scalp

Chronic Mucocutaneous Candidiasis

Candidiasis, Chronic Mucocutaneous	Cmc
Candidiasis Chronic Mucocutaneous

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P5963	Lib2-1	Inhibitor	99.63%	Unkown
HY-RS06706	IL17RE Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	IL17RE	VGNC	VGNC:97464
Mus musculus	IL17RE	MGD	MGI:1889371
Macaca mulatta	IL17RE	VGNC	VGNC:73623
Canis familiaris	IL17RE	VGNC	VGNC:41950
Rattus norvegicus	IL17RE	RGD	RGD:735148
Bos taurus	IL17RE	VGNC	VGNC:30125
Others	IL17RE	NCBI

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