2. Gene
  3. Defa3 - defensin, alpha, 3 Gene

Defa3 - defensin, alpha, 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Defa27; Defcr3; Defcr-3

Gene ID: 13237 | Gene type: protein coding

About Defa3

Summary

Predicted to enable protein homodimerization activity. Acts upstream of or within response to bacterium and response to xenobiotic stimulus. Located in extracellular space. Orthologous to several human genes including DEFA1 (defensin alpha 1); DEFA3 (defensin alpha 3); and DEFA4 (defensin alpha 4). [provided by Alliance of Genome Resources, Apr 2022]

Defa3 Products(1)

mRNA Protein Name
NM_007850.2 NP_031876.1 alpha-defensin 3 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to lipopolysaccharide IGI
IGI: Inferred from genetic interaction
11248802 MGI
acts upstream of or within defense response to Gram-negative bacterium IGI
IGI: Inferred from genetic interaction
11248802 MGI
acts upstream of or within defense response to Gram-positive bacterium IGI
IGI: Inferred from genetic interaction
11248802 MGI
acts upstream of or within defense response to bacterium IDA
IDA: Inferred from direct assay
7927786 MGI
acts upstream of or within response to xenobiotic stimulus IDA
IDA: Inferred from direct assay
11248802 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
11248802 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-defensin 3

defensin, alpha, 27

defensin-related cryptdin-3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03674 DEFA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Defa3 NCBI NCBI:1668